Vulvopure Plus® 60 capsule

Vulvopure Plus®: complete protection against bacterial cystitis, including recurrent and post-coital cystitis

Vulvopure Plus® is a powdered dietary supplement formulated to effectively treat acute, recurrent, and post-coital bacterial cystitis. The most common symptoms of cystitis include burning, increased urinary frequency, urgency, and suprapubic pain. Vulvopure Plus® is formulated to act quickly on these conditions, offering natural and safe relief and prevention.

Vulvopure Plus®, thanks to the synergy between D-mannose , Oximacro® , CalMYR-P Mirra® and xylitol , the product acts on multiple fronts: bacterial adhesion, biofilm, inflammation and pain, offering complete and well-tolerated support.

D-mannose is a simple sugar with a high affinity for the FimH lectins present on the pili of uropathogenic bacteria , particularly Escherichia coli . By binding to these receptors, it prevents their adhesion to the bladder mucosa, promoting their elimination through urination. Its action is mechanical and selective , does not alter the microbiota, and can also be taken by diabetics, as it does not significantly affect blood sugar levels. Its high purity and orosolubility make it rapidly and effectively absorbed.

Oximacro® is a patented extract of Vaccinium macrocarpon , with a high concentration of type A proanthocyanidins (PAC-A), the only bioactive molecules in blueberries with clinically relevant antibacterial properties. PAC-A inhibits the adhesion of bacteria that are not sensitive to D-mannose , such as Klebsiella , Proteus , and Enterococcus , thus broadening the product's spectrum of action. Furthermore, they help reduce recurrence thanks to their synergistic action on the urinary microbiota.

CalMYR-P is a standardized myrrh extract, titrated in furanodienes, sesquiterpenes with documented anti-inflammatory and analgesic activity . These compounds are able to activate opioid receptors and modulate the inflammatory pathways involved in acute cystitis. The inclusion of CalMYR-P in Vulvopure Plus® makes it particularly useful in symptomatic cases, to reduce pain, urinary urgency, and dysuria without resorting to NSAIDs or synthetic analgesics.

Xylitol is a polyol that, in addition to its sweetening function, interferes with the formation of bacterial biofilms , making pathogens more vulnerable to the immune response and the synergistic action of other active ingredients. It is particularly useful against resistant strains or in the presence of mixed infections, where the action of D-mannose alone may not be sufficient.

Why choose Vulvopure Plus®?

• Complete broad-spectrum formula: D-mannose, cranberry PAC-A and xylitol cover a broad spectrum of uropathogenic bacteria, including non-mannose-sensitive ones.
• Synergistic antibacterial and anti-inflammatory action: Counteracts bacterial adhesion, biofilm formation and reduces inflammation and pain associated with acute cystitis.
• Indicated in the acute and preventive phase: Ideal both during episodes of cystitis and to prevent recurrences, including post-coital ones.
• High tolerability and purityFree from gluten, lactose, sugars, heavy metals, and irritating ingredients. Safe even for prolonged use.
• Pharmaceutical quality and Halal certification: Produced in Italy according to GMP standards, with selected and pure raw materials, to guarantee efficacy and safety.

INGREDIENTS Vulvopure Plus®